Browsing Research publications by Author "Martin, G.P."
Now showing items 1-6 of 6
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Discriminating the molecular identity and function of discrete supramolecular structures in topical pharmaceutical formulations
Benaouda, F.; Brown, Marc; Ganguly, S.; Jones, S.A.; Martin, G.P. (2012-09-04)There is a need to understand how solvent structuring influences drug presentation in pharmaceutical preparations, and the aim of this study was to characterize the properties of propylene glycol (PG)/water supramolecular ... -
Evidence for flocculation-controlled microcrystallisation of salmeterol xinafoate
Murnane, D.; Martin, G.P.; Haley, I.; Marriott, C. (2006-09)The therapeutic management of pulmonary disease depends upon the efficient delivery of aerosolized drug particles with an aerodynamic diameter of 2.5–6 mm (Pritchard 2001). Particles for such aerosols are routinely produced ... -
Formation and measurement of process induced disorder during the manufacture of inhalation medicines
Royall, P.G.; Woodhead, B.; Tang, S.J.; Martin, G.P.; Stockton, B.M.; Murnane, D. (2011-07-01)The development and manufacture of inhalation medicines presents a number of complex challenges to the pharmaceutical scientist. Of paramount importance is delivering the drug particles with an optimal size for deposition ... -
Particle aggregation of salmeterol xinafoate (SX) in HFA134a high pressure suspensions
Murnane, D.; Martin, G.P.; Marriott, C. (2006-09) -
Protective mechanism of stabilising excipients against dehydration in the freeze-drying of proteins
Liao, Y.; Brown, Marc; Martin, G.P. (2002)To investigate the influence of type and amount of excipient on the preservation of the native structure and the biologic activity of freeze-dried lysozyme and catalase -
Transdermal drug delivery devices: Skin perturbation systems
Brown, M.B.; Traynor, M.J.; Martin, G.P.; Akomeah, F.K. (Springer (Humana Press), 2008)Human skin serves a protective function by imposing physicochemical limitations to the type of permeant that can traverse the barrier. For a drug to be delivered passively via the skin it needs to have a suitable lipophilicity ...