Browsing Research publications by Author "Postgraduate Medicine"
Now showing items 1-20 of 107
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2-DPMP (desoxypipradrol, 2-benzhydrylpiperidine, 2-phenylmethylpiperidine) and D2PM (diphenyl-2-pyrrolidin-2-yl-methanol, diphenylprolinol) : A preliminary review
Corkery, John; Schifano, Fabrizio; Ghodse, A. Hamid; Elliott, S.; Corazza, Ornella (2012)2-DPMP (desoxypipradrol, 2-benzhydrylpiperidine, 2-phenylmethylpiperidine) and D2PM (diphenyl-2-pyrrolidin-2-yl-methanol, diphenylprolinol) are psychoactive substances, sold primarily over the Internet and in 'head' shops ... -
25C-NBOMe: preliminary data on pharmacology, psychoactive effects and toxicity of a new potent hallucinogenic drug
Bersani, Francesco Saverio; Corazza, Ornella; Albano, Gabriella; Valeriani, Giuseppe; Santacroce, Rita; Bolzan, Flamina; Cinosi, Eduardo; Simonato, Pierluigi; Martinotti, Giovanni; Bersani, Giuseppe; Schifano, Fabrizio (2014-07-03)Introduction. The use of novel psychoactive substances (NPSs) has rapidly increased as well as their online availability. The aim of this paper is to provide a comprehensive review of the nature and the risks associated ... -
A 5 item version of the Compliance Questionnaire for Rheumatology (CQR5) successfully identifies low adherence to DMARDs
Hughes, Lyndsay D.; Done, D.J.; Young, Adam (2013-10)Taking DMARDs as prescribed is an essential part of self-management for patients with Rheumatoid Arthritis. To date, the Compliance Questionnaire for Rheumatology (CQR) is the only self-report adherence measure created ... -
Adjunctive therapies to reduce thrombotic events in patients with a history of myocardial infarction : role of vorapaxar
Farag, Mohamed; Patel, Hiten; Gorog, Diana A (2015-07-22)Acute myocardial infarction (AMI) is generally attributed to coronary atherothrombotic disease. Platelet activation is essential for thrombus formation and is thus an important target for pharmacological intervention to ... -
Adverse psychiatric effects associated with herbal weight-loss products
Bersani, Francesco Saverio; Coviello, Marialuce; Imperatori, Claudio; Francesconi, Marta; Valeriani, Giuseppe; De Stefano, Gianfranco; Bolzan Mariotti Posocco, Flaminia; Santacroce, Rita; Minichino, Amedeo; Corazza, Ornella (2015)Obesity and overeating are among the most prevalent health concerns worldwide and individuals are increasingly using performance and image-enhancing drugs (PIEDs) as an easy and fast way to control their weight. Among ... -
Agreement among optometrists and ophthalmologists in estimating limbal anterior chamber depth using the van Herick method
Jindal, Anish; Myint, Joy; Edgar, David F.; Nolan, Winifred P.; Lawrenson, John G. (2015-03)Purpose: To evaluate the inter-observer agreement for measuring limbal anterior chamber depth (LACD) using the van Herick test in community optometrists, glaucoma specialist optometrists and ophthalmologists. Methods: The ... -
Analisi dei report online relativi al potenziale uso errato della benzidamina
Schifano, Fabrizio; Corazza, Ornella; Marchi, Alessandro; di Melchiorre, Giuditta; Sferrazza, Elias; Enea, Aurora; Davey, Z.; Blaszko, Ursula; Deluca, Paolo (2013)Benzydamine/Tantum Rosa is a drug for external use. It is typically available in Europe, without the need of a medical prescription, for the treatment of vaginal inflammatory processes. Between December 2009 and January ... -
Are low erythropoietin and 1,25-dihydroxyvitamin D levels indicative of tubulo-interstitial dysfunction in diabetes without persistent microalbuminuria?
Singh, D.K.; Winocour, P.; Summerhayes, B.; Viljoen, A.; Sivakumar, G.; Farrington, Ken (2009)Aims: To investigate the relationship between Erythropoietin (EPO) and 1,25-dihydroxyvitamin D levels, and tubular damage in patients with diabetes mellitus (DM) without persistent microalbuminuria. Methods: We measured ... -
An association between depressive symptoms and survival in incident dialysis patients
Chilcot, Joseph; Davenport, Andrew; Wellsted, D.; Firth, John; Farrington, Ken (2011)Depression in end-stage renal disease patients is detrimental to quality of life, and is also associated with adverse clinical outcomes. The aim of this study was to examine whether depression symptoms in 'incident dialysis' ... -
Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis : experience in the ERAN inception cohort
McWilliams, Daniel F.; Kiely, Patrick D. W.; Young, Adam; Walsh, David A. (2013-05)Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors ... -
Can Early, Clinically Significant Radiographic Progression In The First Year Of Disease Predict Orthopaedic Surgery In Patients With Rheumatoid Arthritis?
Carpenter, Lewis; Jayakumar, Keeranur; Nikiphorou, Elena; Norton, Sam; Dixey, Josh; Young, Adam (2014-04)BACKGROUND: Orthopaedic intervention is an important outcome in Rheumatoid Arthritis (RA). The use of radiographic data in the early stages of the disease and its importance in determining future RA related outcomes is ... -
Childhood dermatomyositis recurring in adulthood half a century later
Ismajli, M.; Nikiphorou, E.; Young, Adam (2013-09-02)A 62-year-old woman presented to the emergency department with malaise, lethargy and proximal muscle weakness. She had a similar presentation in childhood. A muscle biopsy was inconclusive, however, she was treated for a ... -
Choosing not to dialyse : evaluation of planned non-dialytic management in a cohort of patients with end-stage renal failure
Smith, C.; Da Silva-Gane, M.; Chandna, S.; Warwicker, P.; Greenwood, R.; Farrington, Ken (2003-10-31)OBJECTIVES: To study factors influencing the recommendation for palliative (non-dialytic) treatment in patients approaching end-stage renal failure and to study the subsequent outcome in patients choosing not to dialyse. ... -
Choosing Not to Take Phosphate Binders : The Role of Dialysis Patients' Medication Beliefs
Wileman, Vari; Chilcot, Joseph; Norton, Sam; Hughes, Lyndsay; Wellsted, D.; Farrington, Ken (2011)Objective: Patients with end-stage renal disease (ESRD) receiving haemodialysis are at risk of cardiovascular disease and bone disorders related to high levels of serum phosphate (PO(4)). Phosphate binders are an important ... -
Communication as care at end of life : An emerging issue from an exploratory action research study of renal end-of-life care for ethnic minorities in the UK
Wilkinson, Emma K.; Randhawa, Gurch; Brown, Edwina Anne; Da Silva Gane, Maria; Stoves, John; Warwick, Graham L.; Akhtar, Tahira; Magee, Regina; Sharman, Sue; Farrington, Ken (2014-09)South Asian people have a higher risk of developing kidney disease, are disproportionately represented in the patient population requiring renal replacement therapy and wait longer to receive a kidney transplant, compared ... -
Consideration of the novel psychoactive substances (‘legal highs’)
Advidory Council on the Misuse of Drugs (Home Office, 2011-08)The Advisory Council on the Misuse of Drugs (ACMD) committed to providing the Government with advice on novel psychoactive substances (often colloquially termed „legal highs‟). This is a relatively recent phenomenon, ... -
Dealing with diversity : cross-cultural aspects of the near death experiences
Corazza, Ornella; Kuruppuarachchi, K.A.L.A. (Jessica Kingsley Publishers, 2011) -
Designer drugs on the Internet : a phenomenon out-of-control? : The emergence of hallucinogenic drug Bromo-Dragonfly
Corazza, Ornella; Schifano, Fabrizio; Farre, Magi; Deluca, Paolo; Davey, Zoe; Drummond, Colin; Torrens, Marta; Demetrovics, Zsolt; Di Furia, Lucia; Flesland, Liv; Mervo, Barbara; Moskalewicz, Jacek; Pisarska, Agnieszka; Shapiro, Harry; Siemann, Holger; Skutle, Arvid; Pezzolesi, Cinzia; van der Kreeft, Peer; Scherbaum, Norbert (2011)Based on the material available in both the scientific literature and on the web, the present paper provides an updated pharmacological, chemical, toxicological and behavioural overview of Bromo-Dragonfly (1-(8-bromobenzo[1,2- ... -
Detecting a signal in the noise : Monitoring the global spread of novel psychoactive substances using media and other open source information
Young, Matthew; Dubeau, C.; Corazza, Ornella (2015-07)To determine the feasibility and utility of using media reports and other open-source information collected by the Global Public Health Intelligence Network (GPHIN), an event-based surveillance system operated by the Public ... -
The diffusion of Performance and Image Enhancing Drugs (PIEDs) on the internet : The abuse of the cognitive enhancer Piracetam
Corazza, Ornella; Bersani, Saverio; Brunoro, Roberto; Valeriani, G.; Martinotti, Giovanni; Schifano, Fabrizio (2014-12-06)Introduction: Performance and image-enhancing drugs (PIEDs), also known as “lifestyle drugs,” are increasingly sold on the Internet to enhance cognitive as well as sexual, muscular, attentive, and other natural capacities. ...