Research publications: Recent submissions
Now showing items 8441-8460 of 9764
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Experiencias de un estudio del pensamiento del profesorado sobre creatividad musical en escuelas de Inglaterra: implicaciones educativas.
(Universidad de Santander, Santander, Spain., 2007) -
Magnetic field configuration at the galactic center investigated by wide-field near-infrared polarimetry : transition from a toroidal to a poloidal magnetic field
(2010)We present a large-scale view of the magnetic field (MF) in the central 2° × 2° region of our Galaxy. The polarization of point sources has been measured in the J, H, and KS bands using the near-infrared polarimetric camera ... -
The supermassive black hole in M84 revisited
(2010)The mass of the central black hole in the giant elliptical galaxy M84 has previously been measured by two groups using the same observations of emission-line gas with the Space Telescope Imaging Spectrograph (STIS) on the ... -
Wiki-based process framework for blended learning
(ACM Press, 2007)With few exceptions, currently published research on the educational use of wikis does not include how the learning activities should be shaped, planned or enforced in a wiki [11]. In this paper we aim to fill that gap by ... -
Stochastic model of template-directed elongation processes in biology
(2010)We present a novel modular, stochastic model for biological template-based linear chain elongation processes. In this model, elongation complexes (ECs; DNA polymerase, RNA polymerase, or ribosomes associated with nascent ... -
Properties of the T8.5 dwarf Wolf 940 B
(2010)We present 7.5-14.2 μm low-resolution spectroscopy, obtained with the Spitzer Infrared Spectrograph, of the T8.5 dwarf Wolf 940 B, which is a companion to an M4 dwarf with a projected separation of 400 AU. We combine these ... -
A Spitzer view of star formation in the Cygnus X North complex
(2010)We present new images and photometry of the massive star-forming complex Cygnus X obtained with the Infrared Array Camera (IRAC) and the Multiband Imaging Photometer for Spitzer (MIPS) on board the Spitzer Space Telescope. ... -
The application of Gaussian processes in the prediction of percutaneous absorption
(2009-09)Objectives The aim was to assess mathematically the nature of a skin permeability dataset and to determine the utility of Gaussian processes in developing a predictive model for skin permeability, comparing it with existing ... -
Effect of occlusion on the percutaneous penetration of linoleic acid and glycerol
(2002)The effect of occlusion on the in vitro percutaneous absorption of linoleic acid was investigated. A greater skin concentration of linoleic acid from an ethanolic vehicle was observed in non-occluded experiments compared ... -
Metabolism of captopril carboxyl ester derivatives for percutaneous absorption
(2009)To determine the metabolism of captopril n-carboxyl derivatives and how this may impact on their use as transdermal prodrugs. The pharmacological activity of the ester derivatives was also characterised in order to compare ... -
Mechanical characterisation and drug permeation properties of tetracaine-loaded bioadhesive films for percutaneous local anaesthesia
(2006)In the development of bioadhesive patch devices for percutaneous local anesthesia, the tensile properties of the films produced after the casting of the gel intermediates is of key importance to the clinical compliance of ... -
A potential anti-implantation and spermicidal strategy : Putative derivatives of nonoxynol-9 and anti-inflammatory agents and their spermicidal activity
(2006)We report the synthesis of novel ester derivatives of nonoxynol-9, an approved spermicidal agent, using the non-steroidal inflammatory drugs (NSAIDs) ibuprofen and indomethacin. Indomethacin has previously been shown to ... -
Design, synthesis and characterisation of captopril prodrugs for enhanced percutaneous absorption
(2006)Most drugs are designed primarily for oral administration, but the activity and stability profiles desirable for this route often make them unsuitable for transdermal delivery. We were therefore interested in designing ... -
Discriminant analysis as a tool to identify compounds with potential as transdermal enhancers
(2005)Structure-activity relationships were sought for 73 enhancers of hydrocortisone permeation from propylene glycol across hairless mouse skin. Enhancers had chain lengths (CC) from 0 to 16 carbon atoms, 1 to 8 H-bonding atoms ... -
Recovering Ga(III) from coordination complexes using pyridine 2,6-dicarboxylic acid chelation ion chromatography
(2010-09)Ion exchange chelation chromatography is an effective means to extract metals from coordination complexes and biological samples; however there is a lack of data to verify the nature of metal complexes that can be successfully ... -
A History of Doughty's Hospital, Norwich, 1687-2009
(University of Hertfordshire Press, 2010)Doughty’s Hospital, an almshouse in Norwich, was founded by a bequest in the will of William Doughty in 1687 and continues to thrive to this day. In this detailed history, the Hospital itself is contextualised within the ... -
Differential Effect of Helicobacter pylori Eradication on Time-Trends in Brady/Hypokinesia and Rigidity in Idiopathic Parkinsonism
(2010)Background: We examine the effect of eradicating Helicobacter in idiopathic parkinsonism (IP). Marked deterioration, where eradication-therapy failed, prompted an interim report in the first 20 probands to reach de-blinding. ...