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Characterisation of ATP-binding cassette (ABC) transporters in the Calu-3 human bronchial epithelial cell culture model

Hutter, Victoria; Hilgendorf, Constanze; Brown, Alan; Cooper, Anne; Zann, Vanessa; Pritchard, David; Bosquillon, Cynthia (2010-10)

Expression and functionality of ATP-binding cassette (ABC) transporters were assessed in Calu-3 cell monolayers cultured at an air-liquid interface. Transporter gene expression was in agreement with published data in human ...

COX-1 or COX-2 deletion is associated with increased nuclear NF-κB in the endothelium of the aortic arch.

Lundberg, Martina; Harrington, Louise Susan; Leadbeater, Phillip D.M.; Warner, Tim D.; Mitchell, Jane A. (2010)

Still and Still Moving : Solo show, video installation

Jury, Samantha (2010-01-06)

The Process Room, Irish Museum of Modern Art, Dublin SASM is a site-specific video project made under the research concerns of 'Fixity and Motion' and part of a series of installations created with projected video into ...

Oral Delivery of Hydrophilic Drugs to the Brain

Centre for Research into Topical Drug Delivery and Toxicology; Nanopharmaceutics; Pharmaceutics; Department of Pharmacy; School of Life and Medical Sciences; Health & Human Sciences Research Institute; Lalatsa, Aikaterini (2010-09-10)

A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes ...

CD recording of works by Raymond Warren. Philip Mead, piano with Seamus Heaney, narrator

Mead, Philip (UH Recordings Ltd, 2010-09)

This is a premiere recording of 'A Lough Neagh Sequence' by Philip Mead, piano, with the poems of Seamus Heaney read by himself. It also includes a recording of the Piano Sonata No 2. Philip Mead worked closely with the ...

Transiently supersaturated solutions from the dissolution of amorphous powders for topical drug delivery

Palmer, I. A.; Jones, S. A.; Murnane, D.; Traynor, M.J.; Moss, Gary; Brown, Marc (2010-06)

The aim of this study was to prepare amorphous forms of clotrimazole to determine whether increasing the rate and extent of dissolution of clotrimazole would result in supersaturated solutions capable of increasing the ...

The Mr. Nile Experiment

Goodbrey, Daniel (2012)

Originally created as a daily improvisation over the course of one month in 2003, Nile served as metafictional platform via which to directly address the reader and express my thinking on the digital comics form. Among the ...

'Lift Up Your Hearts': a Contribution to the Understanding of John Calvin's Teaching on the Eucharist and its Setting Within his Theology

Smith, Allan Robert (University of Hertfordshire, 2015-01-16)

This dissertation considers the possibility that, flowing from his broader theological framework and historical background, John Calvin’s eucharistic theology ‘re-invents’ a doctrine where the ‘substance’ (meaning) of the ...

Strangebook

School of Creative Arts; Art and Design; Media Research Group; Theorising Visual Art and Design; Games and Visual Effects Research Lab (G+VERL); Goodbrey, Daniel (2012)

I was hired by child psychiatrist Christine Kuhn to help develop a prototype iPad app based on her research group’s idea for an interactive comics jam version of Facebook. The focus of Strangebook is on allowing young ...

Happy Birthday Edward Lear : An illustrated tribute by 40 artists

Graff, Adam (2012)

Touring group exhibition starting at the Poetry Society, Covent Garden, London 7th May - 8th June 2012

The counterfeit conundrum

Kirby, M. G.; Kirby, M. (2012-03)

The role of embodiment and intersubjectivity in clinical reasoning

Gallagher, Shaun; Payne, Helen (2015)

Embodied approaches to cognition have been recently challenging standard views in philosophy of mind and the cognitive sciences. We propose that these embodied cognition views hold implications for clinical reasoning. This ...

Arene-fused 1,2-oxazole N-oxides and derivatives. The impact of the N-O dipole and substitution on their aromatic character and reactivity profile. Can it be a useful structure in synthesis? A theoretical insight

Kozielewicz, Paweł; Tzeli, Demeter; Tsoungas, Petros G.; Zloh, Mire (2014-12-01)

DFT calculations have shown that the N-O dipole of benzene- and naphthalene-fused 1,2-oxazole N-oxides causes a distortion of their σ and π frame, concentrated on the 1,2-oxazole ring, such that it increases its susceptibility ...

Intramolecular cyclization of β-nitroso-o-quinone methides : A theoretical endoscopy of a potentially useful innate 'reclusive' reaction

Tzeli, Demeter; Tsoungas, Petros G.; Petsalakis, Ioannis D.; Kozielewicz, Paweł; Zloh, Mire (2015-01-14)

Oxidatively generated β-nitroso-o-quinone methides undergo an o- and/or peri-intramolecular cyclization to arene-fused 1,2-oxazoles, 1,2-oxazines or indoles. The reaction, found to be an innate process, has been scrutinized ...

Computational classification models for predicting the interaction of drugs with P-glycoprotein and breast cancer resistance protein

Erić, S.; Kalinić, M.; Ilić, K.; Zloh, Mire (2014-12)

P-glycoprotein (P-gp/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) are two members of the adenosine triphosphate (ATP) binding cassette (ABC) family of transporters which function as membrane efflux transporters ...

University of Hertfordshire Research Archive