Browsing by Title
Now showing items 15333-15352 of 24089
-
The novel psychoactive substances epidemic: A scientometric perspective
(2023-01-05)The unprecedented proliferation of novel psychoactive substances (NPS) in the illicit drug market has been a public health concern since their emergence in the 2000s. Their consumption can pose severe health risks as their ... -
Novel Psychoactive Substances in Custodial Settings : A Mixed Method Investigation on the Experiences of People in Prison and Professionals Working With Them
(2020-05-26)Introduction: Novel Psychoactive Substances (NPS), especially Synthetic Cannabinoid Receptor Agonists (SCRAs), pose a substantial challenge to health and the security of the prison environment. This study analyses the ... -
Novel psychoactive substances of interest for psychiatry
(2015-02)Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, ... -
Novel Psychoactive Substances: : the pharmacology of stimulants and hallucinogens
(2016-07-02)There are increasing levels of concern relating to the rapidly evolving novel psychoactive substances/NPS and web markets’ scenarios. The paper aims at providing an overview of the clinical pharmacological issues related ... -
Novel Psychoactive Substances: Policy, Economics and Drug Regulation
(Springer Nature, 2017-08-26) -
A Novel Reinforcement-Based Paradigm for Children to Teach the Humanoid Kaspar Robot
(2019-11-22)This paper presents a contribution to the active field of robotics research with the aim of supporting the development of social and collaborative skills of children with Autism Spectrum Disorders (ASD). We present a novel ... -
Novel role for P2X receptor activation in endothelium-dependent vasodilation
(2004-11-01)ATP is an important vasoactive mediator, which acts via two receptor classes: P2X and P2Y. Activation of P2X receptors has traditionally been associated with the well-characterised vasoconstrictor properties of ATP. In the ... -
A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy
(2015-06-22)Introduction: Protein deimination, defined as the post-translational conversion of protein-bound arginine to citrulline, is carried out by a family of 5 calcium-dependent enzymes, the peptidylarginine deiminases (PADs) and ... -
Novel selective compounds for the investigation of imidazoline receptors
(1999-06)Over several years our group has sought to synthesize and identify selective ligands for imidazoline (I) receptors, in particular the I2 binding site. As a consequence, [3H]2-(2-benzofuranyl)-2-imidazoline (2BFI) has proved ... -
A novel self-sintering microparticle-based system for regenerative medicine
(2008-07)The use of injectable scaffolds has raised great interest as they minimise the need for invasive surgery and its associated complications, costs and discomfort to the patient. Furthermore, they can fill cavities of any ... -
Novel Siglec-15-Sia axis inhibitor leads to colorectal cancer cell death by targeting miR-6715b-3p and oncogenes
(2023-10-06)Siglecs are well known immunotherapeutic targets in cancer. Current checkpoint inhibitors have exhibited limited efficacy, prompting a need for novel therapeutics for targets such as Siglec-15. Presently, small molecule ... -
A Novel Signal Processing Method for Friction and Sliding Wear
(2022-05-01)This current study proposed a new computationally efficient and comparatively accurate algorithm for calculating both static and dynamic coefficients of friction from high frequency data. Its scope embraced an application ... -
Novel stem cell technologies are powerful tools to understand the impact of human factors on Plasmodium falciparum malaria
(2023-12-19)Plasmodium falciparum parasites have a complex life cycle, but the most clinically relevant stage of the disease is the invasion of erythrocytes and the proliferation of the parasite in the blood. The influence of human ... -
Novel Synthetic Opioids (NSO) Use in Opioid Dependents Entering Detoxification Treatment
(2022-06-01)Introduction: Over the last decade, the use of New/Novel Synthetic Opioids (NSO) has emerged as an increasing problem, and especially so in the USA. However, only little is known about the prevalence and history of NSO use ... -
Novel systems to study vector-pathogen interactions in malaria
(2023-05-26)Some parasitic diseases, such as malaria, require two hosts to complete their lifecycle: a human and an insect vector. Although most malaria research has focused on parasite development in the human host, the life cycle ...