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Now showing items 16645-16664 of 24122
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Pharmacokinetics and applications of ampicillin sodium as an intravenous infusion in the horse
(1993-03)A regime for administration of ampicillin sodium by continuous intravenous infusions to horses was designed. The aim was to achieve plasma ampicillin concentrations between 5 and 10 micrograms/ml over a 4-h period. A 2 ... -
Pharmacokinetics and clinical effects in dogs of a sustained-release formulation of theophylline
(1993-08)Theophylline was administered orally in a sustained-release preparation at a dose rate of 20 mg/kg bodyweight to six beagle dogs. A mean (+/- se) maximum plasma concentration of 12.2 +/- 0.65 micrograms/ml was obtained ... -
Pharmacokinetics and clinical efficacy of a cinchophen and prednisolone combination in the dog
(1991-02)The kinetics and efficacy of a cinchophen prednisolone combination preparation (PLT) were assessed in the dog. Cinchophen administered at a dose rate of 12-5 mg/kg intravenously had a volume of distribution (Vd area) of ... -
Pharmacokinetics and pharmacodynamics of piroxicam in dogs
(1991-06)Piroxicam was administered to beagle dogs intravenously and orally at a dose rate of 0.3 mg/kg bodyweight. It had an elimination half-life of 40.2 hours, a volume of distribution of 0.29 +/- 0.02 litres/kg and a body ... -
Pharmacokinetics and tissue disposition of danofloxacin in sheep
(1998-03)The plasma pharmacokinetics of danofloxacin administered at 1.25 mg kg(-1) body weight by the intravenous and intramuscular routes were determined in sheep. Tissue distribution was also determined following administration ... -
Pharmacokinetics and tolerance of florfenicol in Equidae
(1996-05)Florfenicol was administered to horses and ponies at a dose rate of 22 mg/kg bwt by i.v., i.m. and oral routes. Following i.v. administration it had an elimination half-life of 1.8 +/- 0.9 h, a body clearance of 0.4 +/- ... -
Pharmacokinetics of a porcine insulin zinc suspension in diabetic dogs
(1997-10)Ten dogs with naturally occurring diabetes mellitus were injected with a highly purified porcine insulin zinc suspension at a dose according to their expected requirement. Plasma insulin and glucose concentrations were ... -
Pharmacokinetics of acetylcholinesterase reactivator K203 and consequent evaluation of low molecular weight antioxidants/markers of oxidative stress
(2012)Oxime K203 is a new compound designed to be used as an acetylcholinesterase reactivator for the treatment of intoxication following exposure to tabun and certain pesticides. After intramuscular administration of a therapeutic ... -
The pharmacokinetics of albendazole metabolites following administration of albendazole, albendazole sulfoxide and netobimin to one-month- and eight-month-old sheep
(1995-10)The principal metabolites detected in plasma of sheep following oral administration of albendazole (ABZ), albendazole sulfoxide (ABSO) and netobimin (NTB) each at 5.0 mg kg-1 body weight were ABSO and albendazole sulfone ... -
Pharmacokinetics of bacampicillin in equids
(1995)Bacampicillin hydrochloride is an ester prodrug that is hydrolyzed to ampicillin after its absorption from the gastrointestinal tract. It was administered intragastrically at a dose rate of 13.5 mg/kg of body weight to ... -
Pharmacokinetics of Bupropion and Its Metabolites in Haemodialysis Patients Who Smoke
(2004)To date, no study has investigated the effects of bupropion (BP) in renal-impaired humans. This study aims to identify the pharmacokinetics of BP and metabolites in haemodialysis patients who smoke, determine whether ... -
Pharmacokinetics of enrofloxacin and danofloxacin in plasma, inflammatory exudate, and bronchial secretions of calves following subcutaneous administration
(1999-08)Enrofloxacin (2.5 mg/kg of body weight) and danofloxacin (1.25 mg/kg) were administered subcutaneously to ruminating calves (n = 8) fitted with subcutaneous tissue cages. Concentrations of enrofloxacin, its metabolite ... -
Pharmacokinetics of fenbendazole in dogs
(1990)Fenbendazole was administered to dogs at a dose rate of 20 mg/kg body weight on a single occasion in gelatin capsules, on 5 consecutive days in feed, and on a single occasion as an alginate suspension. It was also administered ... -
The pharmacokinetics of flunixin meglumine in the sheep
(1993-06)Flunixin meglumine was administered intravenously and intramuscularly in sheep and the pharmacokinetics of the drug studied. Plasma concentrations of flunixin were measured by high performance liquid chromatography. The ... -
Pharmacokinetics of halofuginone in cattle
(1989-11-01)The pharmacokinetics of the antitheilerial drug halofuginone were evaluated in healthy calves following oral administration, at a dose of 1·2 mg/kg body weight, repeated after 48 h. The maximum plasma concentration after ... -
Pharmacokinetics of niclofolan in desert sheep
(1990-06)