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Now showing items 19240-19259 of 24196
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The role of ATP citrate-lyase in the metabolic regulation of plasma lipids. Hypolipidaemic effects of SB-204990, a lactone prodrug of the potent ATP citrate-lyase inhibitor SB-201076
(1998-08-15)ATP citrate (pro-S)-lyase (EC 4.1.3.8), a cytosolic enzyme that generates acetyl-CoA for cholesterol and fatty acid synthesis de novo, is a potential target for hypolipidaemic intervention. Here we describe the biological ... -
The Role of Autonomy and Interaction Type on Spatial Comfort in an HRI Scenario
(University of Hertfordshire, 2008)This extended abstract presents findings from a live HRI study carried out in the UH robot house. The participants (33 in total) were approached by a robot for 3 different interaction types and the amount of control the ... -
Role of bradykinin and platelet-activating factor in mediating lipopolysaccharide-induced vasodilatation in the rat perfused heart
(Portland Press Proceedings, 1994) -
Role of camalexin, indole glucosinolates, and side chain modification of glucosinolate-derived isothiocyanates in defense of Arabidopsis against Sclerotinia sclerotiorum
(2011)Plant secondary metabolites are known to facilitate interactions with a variety of beneficial and detrimental organisms, yet the contribution of specific metabolites to interactions with fungal pathogens is poorly understood. ... -
The role of category information in word identification : a parallel decision-model
(1983)Four experiments consider the role of semantic category information in word identification using a serial classification reaction time paradigm. Experimental variables were manipulated by varying the semantic properties ... -
The Role of Chaos and Self Organisation in Creative Organisations
(Presse de la Universite du Quebec, 1995) -
The role of chasmothecia in the initiation of epidemics
(Association of Applied Biologists, 2013) -
The role of comorbidities alongside patient and disease characteristics in long-term disease activity in RA using UK inception cohort data
(2022-11-30)Objectives Control of disease activity in RA is a crucial part of its management to prevent long-term joint damage and disability. This study aimed to identify early predictors of poor disease activity at 5 and 10 years, ... -
Role of complexes formation between drugs and penetration enhancers in transdermal delivery
(2008-11-03)The use of chemical penetration enhancers (CPE) is growing due to their ability to improve drug delivery through the skin. A possible mechanism of penetration enhancement could involve the complex formation between drug ... -
Role of comprehensive geriatric assessment in healthcare of older people in UK care homes : realist review
(2019-04-08)OBJECTIVES: Comprehensive geriatric assessment (CGA) may be a way to deliver optimal care for care home residents. We used realist review to develop a theory-driven account of how CGA works in care homes. DESIGN: Realist ... -
Role of Core-collapse Supernovae in Explaining Solar System Abundances of p Nuclides
(2018-02-07)The production of the heavy stable proton-rich isotopes between 74Se and 196Hg - the p nuclides - is due to the contribution from different nucleosynthesis processes, activated in different types of stars. Whereas these ... -
Role of COX-1 and COX-2 in the release of prostanoids in murine lung and isolated lung fibroblasts
(2011-06)Cyclooxygenase (COX) is the first enzyme in the conversion of arachidonic acid to prostanoids. There are two isoforms of COX; COX-1, which is constitutively expressed with a homeostatic role in most tissues, and COX-2, ... -
The role of culture and diversity in the prevention of falls among older Chinese people
(2011)This grounded-theory study explored the perceptions of Chinese older people, living in England, on falls and fear of falling, and identified facilitators and barriers to fall prevention interventions. With a sample of 30 ... -
The role of Dementia Champion in dementia care : Its aspirations, development and training needs (innovative practice)
(2016-09-01)Background: The conceptualisation and development of the role of Dementia Champions in clinical practice is on-going, and dementia specific training has a significant impact on the scope of the role. Aim: This survey aimed ...