Browsing University of Hertfordshire by Title
Now showing items 15472-15491 of 24374
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Novel antithrombotic agents for atrial fibrillation
(2012-06-01)Atrial fibrillation (AF) is the most common cardiac arrhythmia. It is estimated that 1 in 4 individuals aged 40 years or above will develop at least 1 episode of AF during their lifetime. Stroke is a leading cause of ... -
A novel approach to isoindolo[2,1-a]indol-6-ones
(2012)A convenient route to isoindolo[2,1-a]indol-6-ones has been developed starting from the appropriate 2-(N-phthaloyl)benzoic acids. Formation of the acid chlorides with thionyl chloride followed by heating with triethyl ... -
A novel approach to the use of genetically modified herbicide tolerant crops for environmental benefit
(2003-02-22)The proposed introduction of genetically modified herbicide tolerant (GMHT) crops, with claims of improved weed control, has prompted fears about possible environmental impacts of their widespread adoption, particularly ... -
A novel approach to the use of genetically modified herbicide tolerant crops for environmental benefit
(2003-02)The proposed introduction of genetically modified herbicide tolerant (GMHT) crops, with claims of improved weed control, has prompted fears about possible environmental impacts of their widespread adoption, particularly ... -
Novel approaches for the analysis of immune reactions in Tunicate and Cnidarian model organisms
(Pensoft Publishers, 2003) -
A novel Bayesian approach for decomposing the radio emission of quasars: I. Modelling the radio excess in red quasars
(2024-03-12)Studies show that both radio jets from the active galactic nuclei (AGNs) and the star formation (SF) activity in quasar host galaxies contribute to the quasar radio emission; yet their relative contributions across the ... -
Novel biodesign enhancements to at-risk traditional building materials
(2022-10-03)Extreme weather conditions increase the frequency of regular maintenance on heritage buildings and cause erosion of traditional materials. Developments in bio-enhanced self-repair materials provide an opportunity to improve ... -
A novel botybirnavirus with a unique satellite dsRNA causes latent infection in Didymella theifolia isolated from tea plants
(2023-12-12)The unique, recently discovered fungus Didymella theifolia specifically infects local varieties of tea plant Camellia sinensis in China, and therefore, the characterization of its mycoviruses is important. Three double-stranded ... -
Novel chemokine receptor inhibition assay
(1998)Ligands MCP-4, MCP-3, RANTES, MCP-2, MCP-1 or eotaxin, has been identified for the G-protein receptor HGBER32. -
The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
(1996-06-25)SR-12813 (tetra-ethyl 2-(3,5-di-tert-butyl-4-hydroxy-phenyl)ethenyl-1,1- bisphosphonate) lowers plasma cholesterol in five species. In this paper we investigate the underlying mechanism using Hep G2 cells. SB-12813 inhibited ... -
A novel concept in enteric coating : a double-coating system providing rapid drug release in the proximal small intestine
(2009-01)A novel double-coating enteric system was developed to accelerate drug release in conditions resembling the upper small intestine. The system comprises an inner coat (partially neutralised EUDRAGIT® L 30 D-55 and organic ... -
A novel coping metal material CoCrCu alloy fabricated by selective laser melting with antimicrobial and antibiofilm properties
(2016-10-01)OBJECTIVE: The aim of this study was to fabricate a novel coping metal CoCrCu alloy using a selective laser melting (SLM) technique with antimicrobial and antibiofilm activities and to investigate its microstructure, ... -
A novel double-coating approach for improved pH-triggered delivery to the ileo-colonic region of the gastrointestinal tract
(2010)Oral pH-responsive systems for drug delivery to the ileo-colonic region of the gastrointestinal tract show poor site specificity. Here, we describe a novel double-coating concept, based on the acrylic polymer EUDRAGIT® S, ... -
Novel Drugs, Novel Solutions : Exploring the potential of technological tools for prevention of drug abuse
(2011-07)Objectives: Drug abuse has increased markedly in the last decade especially with the emerging of the unregulated websites selling novel herbal, designer and pharmaceutical psychoactive products. These are advertised online ... -
A novel dsRNA element isolated from the Aspergillus foetidus mycovirus complex
(2013-12)Aspergillus foetidus virus (AfV) contains at least two icosahedral particle types named AfV-fast (-F) and AfV-slow (-S), based on relative electrophoretic mobility. AfV-F is a quadripartite double-stranded RNA (dsRNA) ... -
A Novel Ensemble Machine Learning and an Evolutionary Algorithm in Modeling the COVID-19 Epidemic and Optimizing Government Policies
(2022-02-04)The spread of the COVID-19 disease has prompted a need for immediate reaction by governments to curb the pandemic. Many countries have adopted different policies and studies are performed to understand the effect of each ... -
A Novel Epigenetic Strategy to Concurrently Block Immune Checkpoints PD-1/PD-L1 and CD155/TIGIT in Hepatocellular Carcinoma
(2024-04-17)Tumor microenvironment is an intricate web of stromal and immune cells creating an immune suppressive cordon around the tumor. In hepatocellular carcinoma (HCC), Tumor microenvironment is a formidable barrier towards novel ... -
A novel fast inter mode decision algorithm based on statistic and adaptive adjustment for H.264/AVC
(Institute of Electrical and Electronics Engineers (IEEE), 2007)The advanced video coding (AVC) standard H.264 achieves better video compression performance compared with the previous standards, and one of major features is variable block sizes based mode decision (MD). However, the ... -
Novel fluorescent amphiphilic poly(allylamine) and their supramacromolecular self-assemblies in aqueous media.
(2012)Fluorescent amphiphilic polymers were produced by grafting different types and levels of hydrophobic pendant groups with intrinsic fluorescent properties (fluorenylmethoxy carbonyl (Fmoc), dimethylamino-1-naphthalenesulfonyl ...