Browsing University of Hertfordshire by Title
Now showing items 21518-21537 of 24186
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Synthesis of genomic and subgenomic RNAs by a membrane-bound RNA-dependent RNA polymerase isolated from oat plants infected with cereal yellow dwarf virus
(2006-11)A membrane-bound RNA-dependent RNA polymerase (RdRp) complex was isolated by differential sedimentation from oat plants infected with cereal yellow dwarf virus (CYDV). When incubated with P-32-labelled UTP, unlabelled ATP, ... -
Synthesis of mucoadhesive thiol-bearing microgels from 2-(acetylthio) ethylacrylate and 2-hydroxyethylmethacrylate : novel drug delivery systems for chemotherapeutic agents to the bladder
(2015-07-21)Thiol-bearing microgels have been synthesised from copolymerisation of 2-(acetylthio)ethylacrylate and 2-hydroxyethylmethacrylate, and subsequent deprotection using sodium thiomethoxide. The concentration of thiol groups ... -
The synthesis of potential anti parasitic compounds
(University of Hertfordshire, 2001)Novel members of a homologous series of N', N'-di-(2,6-dinitro-4-trifluoromethylphenyl) diamine dimers related to the anti-malarial compound trifluralin (2,6-dinitro-(N, Ndipropylamino- 4-trifluoromethyl)benzene) have ... -
Synthesis of qualitative research studies regarding the factors surrounding UK critical care trial infrastructure
(2019-12-22)Conducting clinical trials in critical care is integral to improving patient care. Unique practical and ethical considerations exist in this patient population that make patient recruitment challenging, including narrow ... -
Synthesis, biological evaluation, and SAR studies of 14β-phenylacetyl substituted 17-cyclopropylmethyl-7, 8-dihydronoroxymorphinones derivatives : Ligands with mixed NOP and opioid receptor profile
(2018-09-19)A series of 14β-acyl substituted 17-cyclopropylmethyl-7,8-dihydronoroxymorphinone compounds has been synthesized and evaluated for affinity and efficacy for mu (MOP), kappa (KOP), and delta (DOP) opioid receptors and ... -
Synthesis, characterization and biological evaluation of benzo[d]isothiazole ring systems, fused to nitrogen heterocycles
(University of Hertfordshire, 2014-09-19)We have developed a simple and efficient synthetic route, starting from easily available starting materials, to the novel ring system benzo[4,5]isothiazolo[2,3-a]pyrazine-6,6-dioxide. A series of chalcones were synthesized ... -
Synthesis, luminescence and phase composition of samarium-doped zinc phosphate glass ceramics
(2013-06)Samarium doped zinc phosphates ySm2O3–(72–y)ZnO–28P2O5 where y varies between 0·03 and 0·28 mol% were synthesised using the melt quenching method and investigated by photoluminescence, powder x-ray diffraction, differential ... -
Synthetic 26Al emission from galactic-scale superbubble simulations
(2019-10-03)Emission from the radioactive trace element 26Al has been observed throughout the Milky Way with the COMPTEL and INTEGRAL satellites. In particular the Doppler shifts measured with INTEGRAL connect 26Al with superbubbles, ... -
Synthetic cannabinoid use in a case series of patients with psychosis presenting to acute psychiatric settings : Clinical presentation and management issues
(2018-07-14)Background: Novel Psychoactive Substances (NPS) are a heterogeneous class of synthetic molecules including synthetic cannabinoid receptor agonists (SCRAs). Psychosis is associated with SCRAs use. There is limited knowledge ... -
Synthetic Cannabinoids : psychopharmacology, clinical aspects, and psy-chotic onset
(2017-04-13)Synthetic Cannabinoids (SC) are the widest and most diffused class of Novel Psychoactive Substances. SC are chemically heterogeneous and structurally dissimilar from delta-9-tetrahydrocannabinol, being full agonists of the ... -
Synthetic cathinones – prevalence and motivations for use
(Springer Nature, 2018)This chapter considers the prevalence of and motivations for use of synthetic cathinones. As part of the scene-setting, the availability, legal status, numbers of cathinones, number and quantities confiscated are reviewed. ... -
Synthetic Observations of Line Emission from Simulated HII Regions
(2021-03-24)In this work I post-process a series of simulations of Giant Molecular Clouds (GMC) from Dale (2017), Dale et al. (2014) by running them through MOCASSIN (MOnte CArlo SimulationS of Ionized Nebulae) and studying the ... -
Synthetic observations of simulated Pillars of Creation
(2012-02-11)We present synthetic observations of star-forming interstellar medium structures obtained by hydrodynamic calculations of a turbulent box under the influence of an ionizing radiation field. The morphological appearance of ... -
Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2)
(2013-06-27)We demonstrate the first application of synthetic RNA gene silencers in Streptomyces coelicolor A3(2). Peptide nucleic acid and expressed antisense RNA silencers successfully inhibited actinorhodin production. Synthetic ... -
System dynamic simulation of treatment policies to address colliding epidemics of tuberculosis, drug resistant tuberculosis and injecting drug users driven HIV in Russia
(2010)The explosive increase in the number of people infected with tuberculosis (TB), multi drug resistant tuberculosis (MDRTB), and injecting drug users (IDU) HIV/AIDS has become a serious public health challenge in Russia. The ... -
System Dynamics modelling to formulate policy interventions to optimise antibiotic prescribing in hospitals
(2020-08-07)Multiple strategies have been used in the National Health System (NHS) in England to reduce inappropriate antibiotic prescribing and consumption in order to tackle antimicrobial resistance. These strategies have included, ... -
A system for reducing imprecision in speech interfaces to generalised text input devices
(University of Hertfordshire, 1991)This paper reports on ongoing research at Hatfield, where the Speech and Language Technology Group are developing a series of demonstrator systems in order to investigate human-computer interface design for systems where ...