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Browsing University of Hertfordshire by Author "Lou, Fang"
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2,3-Butanedione monoxime increases speed of relaxation in single muscle fibres of frog
Sun, Y-B.; Lou, Fang; Edman, K.A.P. (2001-05)The effects of 2,3-butanedione monoxime (BDM) on intracellular Ca2+ transient and cross-bridge function were studied in frog single fibres from the anterior tibialis muscle of Rana temporaria (sarcomere length, 2.2 microm; ... -
Calcium- and myosin-dependent changes in troponin structure during activation of heart muscle
Sun, Y-B.; Lou, Fang; Irving, M. (2009)Each heartbeat is triggered by a pulse of intracellular calcium ions which bind to troponin on the actin-containing thin filaments of heart muscle cells, initiating a change in filament structure that allows myosin to bind ... -
Changes in force and stiffness induced by fatigue and intracellular acidification in frog muscle fibres
Edman, K.A.P.; Lou, Fang (1990-05)1. Changes in force and stiffness were recorded simultaneously during 1 s isometric (fixed ends) tetani of single fibres isolated from the anterior tibialis muscle of Rana temporaria (temperature 1-3 degrees C; sarcomere ... -
Contraction with shortening during stimulation or during relaxation : how do the energetic costs compare?
Lou, Fang; Curtin, N.A.; Woledge, R.C. (1998-10)White muscle fibres from dogfish were used to compare the energetic costs of shortening by fully active muscle and by relaxing muscle. The muscle preparation was tetanized for 0.6 s and shortened either during stimulation ... -
Depression of tetanic force induced by loaded shortening of frog muscle fibres
Edman, K.A.P; Caputo, C.; Lou, Fang (1993-07)1. Single fibres isolated from the anterior tibialis muscle of Rana temporaria were allowed to shorten against a high load during a 2.5-4.0 s fused tetanus (1-3 degrees C) and the maximum force produced at the short length ... -
Distinguishing Metabolic Heat from Condensation Heat during Muscle Recovery
Lou, Fang; Curtin, N.A.; Woledge, R.C. (1998)When a thermopile is used to measure the heat production of isolated muscle, the muscle is surrounded by gas saturated with water vapour, initially in equilibrium with the muscle. After contraction, the osmolarity of the ... -
The effects of 2,3-butanedione monoxime (BDM) on the force-velocity relation in single muscle fibres of the frog
Sun, Y-B.; Lou, Fang; Edman, K.A.P. (1995-04)The effects of 2,3-butanedione monoxime (BDM) on the force-velocity relation were studied in single fibres from the anterior tibialis muscle of Rana temporaria (2.2 microns sarcomere length, temperature 1.9-2.4 degrees C). ... -
Efficient Assessments : the Assessment Comparator a tool to calculate efficiency
Gormley-Fleming, Elizabeth; Lou, Fang (2013) -
Elastic energy storage and release in white muscle from dogfish scyliorhinus canicula
Lou, Fang; Curtin, N.A.; Woledge, R.C. (1999-01)The production of work by the contractile component (CC) and the storage and release of work in the elastic structures that act in series (the series elastic component, SEC) with the contractile component were measured ... -
The Energetic Cost of Activation of White Muscle Fibres from the Dogfish Scyliophinus Canicula
Lou, Fang; Curtin, N.A.; Woledge, R.C. (1997)The energetic cost of activation was measured during an isometric tetanus of white muscle fibres from the dogfish Scyliorhinus canicula. The total heat production by the fibres was taken as a measure of the total energetic ... -
Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse
Lu, Qi Long; Mann, Christopher J; Lou, Fang; Bou-Gharios, George; Morris, Glenn E; Xue, Shao-an; Fletcher, Sue; Partridge, Terence A; Wilton, Stephen D (2003)As a target for gene therapy, Duchenne muscular dystrophy (DMD) presents many obstacles but also an unparalleled prospect for correction by alternative splicing. The majority of mutations in the dystrophin gene occur in ... -
Heat production and oxygen consumption during metabolic recovery of white muscle fibres from the dogfish Scyliorhinus canicula
Lou, Fang; van Der Laarse, W. J.; Curtin, N.A.; Woledge, R.C. (2000-04)Oxygen consumption and heat production were measured during contraction and recovery of isolated, white muscle fibres from dogfish (Scyliorhinus canicula) at 19 degrees C. The contraction period consisted of 20 isometric ... -
The high-force region of the force-velocity relation in frog skinned muscle fibres
Lou, Fang; Sun, Y-B. (1993-07)The force-velocity relation has been studied during calcium-induced contracture of chemically skinned fibres from the semitendinosus muscle of Rana temporaria with special interest focused on the high-load region. The ... -
Introduction to electronic voting systems: how to use TurningPoint
Lou, Fang; Lorimer, J. (2010)The place of formative assessment within learning has long been established (Draper 2009, Nicol and Mcfarlane-Dick, 2006) and electronic voting systems (EVS) are an easy to use technology that allows lecturers to incorporate ... -
Isometric and isovelocity contractile performance of red muscle fibres from the dogfish Scyliorhinus canicula
Lou, Fang; Curtin, N.A.; Woledge, R.C. (2002-06)Maximum isometric tetanic force produced by bundles of red muscle fibres from dogfish, Scyliorhinus canicula (L.), was 142.4+/-10.3 kN m(-2) (N=35 fibre bundles); this was significantly less than that produced by white ... -
Moderate fatigue studied at great sarcomere lengths in frog single muscle fibres
Lou, Fang; Sun, Y-B. (1994-10)Single fibres from the anterior tibialis muscle of Rana temporaria (temperature, 2-3 degrees C) were moderately fatigued at a prestretched sarcomere length (approximately 3.6 microns) by reducing the intervals between 2 s ... -
Myofibrillar fatigue versus failure of activation during repetitive stimulation of frog muscle fibres
Edman, K.A.P.; Lou, Fang (1992-11)1. Single fibres isolated from the anterior tibialis muscle of Rana temporaria (temperature, 2-5 degrees C; sarcomere length, 2.10 microns) were fatigued using two separate protocols that led to different degrees of ... -
Peer assessment : educationally effective and resource efficient
Barefoot, Helen; Lou, Fang; Russell, M. (2011)Peer assessment was included within a Level 4 Human Physiology module at the Univer-sity of Hertfordshire following a periodic programme review during the academic year 2006-2007. The peer assessment exercise was thought ... -
The potential for online peer assessment : reflections from two modules
Lou, Fang; Bennett, Steve; Barker, Trevor (2012-12)The work described in this presentation relates to the evolution of peer assessment in first year undergraduate students in Life Sciences and Computer Science at the University of Hertfordshire. The objective of this ... -
The relationship between the intracellular Ca2+ transient and the isometric twitch force in frog muscle fibres
Sun, Y-B.; Lou, Fang; Edman, K.A.P. (1996-09)The calcium-sensitive fluorescent indicator fluo-3 was used to monitor the intracellular free calcium concentration ([Ca2+]i) during isometric twitches in twenty-nine single muscle fibres from the anterior tibialis muscle ...