Search
Now showing items 11-20 of 28
Decoding odor quality and intensity in the Drosophila brain
(2014-12-16)
To internally reflect the sensory environment, animals create neural maps encoding the external stimulus space. From that primary neural code relevant information has to be extracted for accurate navigation. We analyzed ...
Automatic segmentation of odor maps in the mouse olfactory bulb using regularized non-negative matrix factorization
(2014-09-01)
Segmentation of functional parts in image series of functional activity is a common problem in neuroscience. Here we apply regularized non-negative matrix factorization (rNMF) to extract glomeruli in intrinsic optical ...
Incretin-modulated beta cell energetics in intact islets of Langerhans
(2014-06-01)
Incretins such as glucagon-like peptide 1 (GLP-1) are released from the gut and potentiate insulin release in a glucose-dependent manner. Although this action is generally believed to hinge on cAMP and protein kinase A ...
The Green's function formalism as a bridge between single- and multi-compartmental modeling
(2013-12)
Neurons are spatially extended structures that receive and process inputs on their dendrites. It is generally accepted that neuronal computations arise from the active integration of synaptic inputs along a dendrite between ...
Peptide pills for brain diseases? : Reality and future perspectives
(2013-04)
The peptide therapeutic market is one of the fastest growth areas of the pharmaceutical industry. Although few orally administered peptides are marketed and many are in different phases of clinical development, there is ...
In vivo decontamination of the nerve agent VX using the domestic swine model
(2012-11)
The purpose of this in vivo study was to assess a new, putatively optimised method for mass casualty decontamination ("ORCHIDS protocol") for effectiveness in removing the chemical warfare agent VX from the skin of ...
Tissue transglutaminase (TG-2) modified amniotic membrane : a novel scaffold for biomedical applications
(2012-08)
The amniotic membrane (AM) is considered as a natural cell culture substrate and has occasionally been exploited in regenerative medicine especially for ocular surface reconstruction and dermal wound healing applications. ...
Neuroinflammation : modulation by flavonoids and mechanisms of action
(2012-02)
Neuroinflammatory processes are known to contribute to the cascade of events culminating in the neuronal damage that underpins neurodegenerative disorders such as Parkinson's and Alzheimer's disease. Recently, there has ...
The generation of phase differences and frequency changes in a network model of inferior olive subthreshold oscillations
(2012)
It is commonly accepted that the Inferior Olive (IO) provides a timing signal to the cerebellum. Stable subthreshold oscillations in the IO can facilitate accurate timing by phase-locking spikes to the peaks of the ...