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Now showing items 21732-21751 of 24445
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Synthesis and Antimicrobial Activity of 1,2-Benzothiazine Derivatives
(2016-06-30)A number of 1,2-benzothiazines have been synthesized in a three-step process. Nine chalcones 1-9 bearing methyl, fluoro, chloro and bromo substituents were chlorosulfonated with chlorosulfonic acid to generate the chalcone ... -
The Synthesis and Biological Evaluation of Novel Nitrogen Containing 6 and 7 Membered Ring Heterocyclic Compounds
(University of Hertfordshire, 2014-05-29)Literature reports have previously shown interesting antimicrobial activities of compounds containing the α,β unsaturated carbonyl function and various piperidone and tropanone derivatives have attracted interest. A series ... -
Synthesis and characterization of absorption-enhanced alumina solid particle materials for direct irradiation solar-thermal conversion
(2024-04-26)Based on solar-thermal application more than 1000 °C, a novel combination of sol-gel synthesis and stepwise calcination to prepare metal-ion doped alumina composite particles as heat transfer media were proposed, enhancing ... -
Synthesis and conformational dynamics of tricyclic pyridones containing a fused seven-membered ring
(2002-12-27)A new synthetic approach to tricyclic pyridones bearing a fused seven-membered ring is described. These compounds exhibit atropisomerism and exist in enantiomeric forms. Chiral HPLC separation of the enantiomers has allowed ... -
Synthesis and Evaluation of Novel Antifungal Agents Targeting the Fungal Plasma Membrane H+-ATPase
(2020-04-06)Fungal infections now contribute significantly to microbe-related morbidity and mortality due to there being a limited number of available antifungal agents and limited modes of delivery. Over the past two decades, many ... -
Synthesis and in silico modelling of the potential dual mechanistic activity of small cationic peptides potentiating the antibiotic novobiocin against susceptible and multi-drug resistant Escherichia coli
(2020-11-30)Cationic antimicrobial peptides have attracted interest, both as antimicrobial agents and for their ability to increase cell permeability to potentiate other antibiotics. However, toxicity to mammalian cells and complexity ... -
Synthesis and optical properties of composite films from P3HT and sandwich-like Ag-C-Ag nanoparticles
(2015-09)Sandwich-like Ag-C-Ag nanoparticles (Ag-C-Ag NPs) were synthesized under mild hydrothermal conditions in a one-step method. With this approach, Ag was not only encapsulated in the centre of an individual carbon nanosphere, ... -
Synthesis and properties of a biodegradable polymer-drug conjugate: Methotrexate-poly(glycerol adipate)
(2018-07-01)Polymer-drug conjugates have been actively developed as potential anticancer drug delivery systems. In this study, we report the first polymer-anticancer drug conjugate with poly(glycerol adipate) (PGA) through the successful ... -
Synthesis and solution properties of a temperature-responsive PNIPAM–b-PDMS–b-PNIPAM triblock copolymer
(2017-08-31)In this paper, we report the synthesis and self-assembly of a novel thermoresponsive PNIPAM60–b-PDMS70–b-PNIPAM60 triblock copolymer in aqueous solution. The copolymer used a commercially available precursor modified with ... -
Synthesis and Spectral Characterization of Benzo[6,7] [1,5]diazocino[2,1-a]isoindol-12-(14H)-one Derivatives
(2016-07-23)A simple synthetic route to benzo[6,7][1,5]diazocino[2,1-a]isoindol-12(14H)-one ring system is developed from readily available starting materials 3-(2-oxo-2-phenylethyl) isobenzofuran-1(3H)-ones and 2-(aminomethyl)aniline ... -
Synthesis gas as a fuel for internal combustion engines in transportation
(2022-05-01)The adverse environmental impact of fossil fuel combustion in engines has motivated research towards using alternative low-carbon fuels. In recent years, there has been an increased interest in studying the combustion of ... -
Synthesis of benzofurans and benzopyrans
(University of Hertfordshire, 2002)Syntheses of 2,3-dihydrobenzofurans and 3,4-dihydrobenzopyrans normally involve several stages, therefore efficient syntheses of these compounds are desirable. A number of 3,4-dihydrobenzopyrans derivatives were prepared ... -
Synthesis of bioinorganic antimicrobial peptide nanoparticles with potential therapeutic properties
(2008)Amphiphilicity and cationicity are properties shared between antimicrobial peptides and proteins that catalyze biomineralization reactions. Merging these two functionalities, we demonstrate a reaction where a cationic ... -
Synthesis of conformationally constrained analogues of BRL32872 : Determination of stereochemistry and related pharmacological properties
(1997-08-05)2-Azabicyclo[2.2.2]octane derivatives have been used as conformationally constrained structure of BRL-32872, in order to investigate the effect of molecular flexibility towards class III and class IV antiarrhythmic properties. ... -
Synthesis of DNA-directed pyrrolidinyl and piperidinyl confined alkylating chloroalkylaminoanthraquinones : potential for development of tumor-selective N-oxides
(2006)A novel series of 1,4-disubstituted chloroethylaminoanthraquinones, containing alkylating chloroethylamino functionalities as part of a rigid piperidinyl or pyrrolidinyl ring-system, have been prepared. The target compounds ... -
Synthesis of Fock states via beam splitters
(1997)An idea to synthesize Fock states for pulsed light beams is presented. It uses an array of beam splitters with several input ports which are fed with single-photon Fock states. Detectors survey all but one output port of ... -
Synthesis of genomic and subgenomic RNAs by a membrane-bound RNA-dependent RNA polymerase isolated from oat plants infected with cereal yellow dwarf virus
(2006-11)A membrane-bound RNA-dependent RNA polymerase (RdRp) complex was isolated by differential sedimentation from oat plants infected with cereal yellow dwarf virus (CYDV). When incubated with P-32-labelled UTP, unlabelled ATP, ...