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Now showing items 11-20 of 106
Pharmacodynamics and pharmacokinetics of tolfenamicacid in ruminating calves: Evaluation in models of acute inflammation
(1998-05)
Injections of mild irritants intradermally (carrageenan, zymosan and dextran) and intracaveally (carrageenan)in a tissue cage model of inflammation were used in studies of the pharmacodynamics and pharmacokinetics of ...
Pharmaceutical quality of anthelmintics sold in Kenya
(1998-04)
Nine anthelmintic products purchased in pharmacies and from agricultural merchants in Kenya were tested for pharmaceutical quality. The concentration of active drug was compared with the claim on the label, and the variability ...
Comparative field evaluation of divided-dosing and reduced feed intake upon treatment efficacy against resistant isolates of Teladorsagia circumcincta in sheep and goats
(1998-03)
The effects of modifying drug administration and food intake upon the efficacy of fenbendazole against resistant isolates of Teladorsagia (Ostertagia) circumcincta were investigated using naturally infected sheep and goats. ...
Pharmacokinetics and tissue disposition of danofloxacin in sheep
(1998-03)
The plasma pharmacokinetics of danofloxacin administered at 1.25 mg kg(-1) body weight by the intravenous and intramuscular routes were determined in sheep. Tissue distribution was also determined following administration ...
The effects of excretions/secretions of Ostertagia circumcincta on ovine abomasal tissues in vitro
(1998-03)
Products excreted/secreted by Ostertagia circumcincta stimulated the in vitro release of pepsinogen from intact abomasal mucosal sheets and caused the contraction of strips of abomasal smooth muscle, also in vitro. However, ...
The influence of dietary supplementation with urea on resilience and resistance to infection with Haemonchus contortus
(1998-01)
Previous research has indicated that supplementing an apparently adequate diet with additional protein improves both host resistance and resilience in lambs infected with Haemonchus contortus. The present study tested the ...
Ecotoxicology and residues of anthelmintic compounds
(1997-11)
Anthelmintics and endectocides used for the treatment and prophylaxis of Ostertagia sp. in ruminants include benzimidazoles, levamisole, morantel and the avermectins and milbemycins. Most of these agents are excreted to ...
Pharmacokinetics of a porcine insulin zinc suspension in diabetic dogs
(1997-10)
Ten dogs with naturally occurring diabetes mellitus were injected with a highly purified porcine insulin zinc suspension at a dose according to their expected requirement. Plasma insulin and glucose concentrations were ...
How hosts control worms
(1997-09-04)
Nematodes are a major cause of disease and death in humans, domestic animals and wildlife. Understanding why some individuals suffer severely whereas others exposed to the same infection remain healthy may assist in the ...
The genetic basis of resistance to Ostertagia circumcincta in lambs
(1997-09)
The relationship between Ostertagia (Teladorsagia) circumcincta and sheep is one of the best understood host-parasite relationships in any species. The key components of resistance have been quantified, the extent of genetic ...