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Now showing items 15308-15327 of 24108
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A novel botybirnavirus with a unique satellite dsRNA causes latent infection in Didymella theifolia isolated from tea plants
(2023-12-12)The unique, recently discovered fungus Didymella theifolia specifically infects local varieties of tea plant Camellia sinensis in China, and therefore, the characterization of its mycoviruses is important. Three double-stranded ... -
Novel chemokine receptor inhibition assay
(1998)Ligands MCP-4, MCP-3, RANTES, MCP-2, MCP-1 or eotaxin, has been identified for the G-protein receptor HGBER32. -
The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
(1996-06-25)SR-12813 (tetra-ethyl 2-(3,5-di-tert-butyl-4-hydroxy-phenyl)ethenyl-1,1- bisphosphonate) lowers plasma cholesterol in five species. In this paper we investigate the underlying mechanism using Hep G2 cells. SB-12813 inhibited ... -
A novel concept in enteric coating : a double-coating system providing rapid drug release in the proximal small intestine
(2009-01)A novel double-coating enteric system was developed to accelerate drug release in conditions resembling the upper small intestine. The system comprises an inner coat (partially neutralised EUDRAGIT® L 30 D-55 and organic ... -
A novel coping metal material CoCrCu alloy fabricated by selective laser melting with antimicrobial and antibiofilm properties
(2016-10-01)OBJECTIVE: The aim of this study was to fabricate a novel coping metal CoCrCu alloy using a selective laser melting (SLM) technique with antimicrobial and antibiofilm activities and to investigate its microstructure, ... -
A novel double-coating approach for improved pH-triggered delivery to the ileo-colonic region of the gastrointestinal tract
(2010)Oral pH-responsive systems for drug delivery to the ileo-colonic region of the gastrointestinal tract show poor site specificity. Here, we describe a novel double-coating concept, based on the acrylic polymer EUDRAGIT® S, ... -
Novel Drugs, Novel Solutions : Exploring the potential of technological tools for prevention of drug abuse
(2011-07)Objectives: Drug abuse has increased markedly in the last decade especially with the emerging of the unregulated websites selling novel herbal, designer and pharmaceutical psychoactive products. These are advertised online ... -
A novel dsRNA element isolated from the Aspergillus foetidus mycovirus complex
(2013-12)Aspergillus foetidus virus (AfV) contains at least two icosahedral particle types named AfV-fast (-F) and AfV-slow (-S), based on relative electrophoretic mobility. AfV-F is a quadripartite double-stranded RNA (dsRNA) ... -
A Novel Ensemble Machine Learning and an Evolutionary Algorithm in Modeling the COVID-19 Epidemic and Optimizing Government Policies
(2022-02-04)The spread of the COVID-19 disease has prompted a need for immediate reaction by governments to curb the pandemic. Many countries have adopted different policies and studies are performed to understand the effect of each ... -
A novel fast inter mode decision algorithm based on statistic and adaptive adjustment for H.264/AVC
(Institute of Electrical and Electronics Engineers (IEEE), 2007)The advanced video coding (AVC) standard H.264 achieves better video compression performance compared with the previous standards, and one of major features is variable block sizes based mode decision (MD). However, the ... -
Novel fluorescent amphiphilic poly(allylamine) and their supramacromolecular self-assemblies in aqueous media.
(2012)Fluorescent amphiphilic polymers were produced by grafting different types and levels of hydrophobic pendant groups with intrinsic fluorescent properties (fluorenylmethoxy carbonyl (Fmoc), dimethylamino-1-naphthalenesulfonyl ... -
Novel gene loci associated with susceptibility or cryptic quantitative resistance to Pyrenopeziza brassicae in Brassica napus
(2023-03-23)Key message Quantitative disease resistance (QDR) controls the association of the light leaf spot pathogen with Brassica napus; four QDR loci that were in linkage disequilibrium and eight gene expression markers were ... -
Novel glass-ceramic composition as sealant for SOFCs
(2014-12-10)This work deals with the design, the characterization, and testing of a novel glass-ceramic to be used as sealant for planar solid oxide fuel cells and its compatibility with Mn1.5Co1.5O4-coated Crofer22APU. Thermal, ... -
Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing
(2015-07-21)Glycopolymer hydrogels capable of mimicking mucosal tissue in mucoadhesion testing have been designed. Liquid formulations containing mucoadhesive polymers were found to be retained on these tissues to the same extent as ... -
A novel healthcare resource allocation decision support tool: A forecasting-simulation-optimization approach
(2020-02-03)The increasing pressures on the healthcare system in the UK are well documented. The solution lies in making best use of existing resources (e.g. beds), as additional funding is not available. Increasing demand and capacity ... -
A Novel High Linearity and Low Power Folded CMOS LNA for UWB Receivers
(2018-03)This paper presents a high linearity and low power Low-Noise Amplifier (LNA) for Ultra-Wideband (UWB) receivers based on CHRT 0.18μm CMOS technology. In this work, the folded topology is adopted in order to reduce the ... -
A novel hybrid energy system combined with solar-road and soil-regenerator: Dynamic model and operational performance
(2018-01-15)Solar roads are emergent and huge energy source in traffic domains. To improve the energy utilization efficiency of a solar road, a novel solar-road and soil-regenerator hybrid energy system in combination with conventional ... -
A Novel Instrument for Studying the Flow Behaviour of Erythrocytes through Microchannels Simulating Human
(1997)A novel instrument has been developed to study the microrheology of erythrocytes as they flow through channels of dimensions similar to human blood capillaries. The channels are produced in silicon substrates using ... -
Novel instrumentation and biomedical applications of very near-infrared fluorescence
(1993-04)A high wavelength fluorescent probe, Nile Red, was added to four proteins, viz., bovine albumin, alpha1-acid glycoprotein, beta-lactoglobulin and ovomucoid. Nile Red showed an enhancement in fluorescence and a shift in ... -
Novel integrated agricultural land management approach provides sustainable biomass feedstocks for bioplastics and supports the UK’s “net-zero” target
(2020-12-28)We investigate the potential in producing biodegradable bio-plastics to support the emergent 'net-zero' greenhouse gas (GHG) emissions targets in the UK. A 'cradle to grave' life cycle assessment was developed to evaluate ...